Using anxiolytics in epilepsy: neurobiological, neuropharmacological and clinical aspects

Neuropharmacological Aspects of Cognitive Neurorehabilitation in Epilepsy

The role of CNS neuromodulators in cognitive neurorehabilitation can be related to two main issues: 1) the negative impact on cognition of drug categories prescribed for different neurologic symptoms, such as spasticity, extrapyramidal symptoms, or epileptic seizures; 2) their possible role in neuroprotection and amelioration of the cognitive status of the patient, especially attention and memo...

Alcohol and suicide: neurobiological and clinical aspects.

Alcohol, primarily in the form of ethyl alcohol (ethanol), has occupied an important place in the history of humankind for at least 8,000 years. In most Western societies, at least 90% of people consume alcohol at some time during their lives, and 30% or more of drinkers develop alcohol-related problems. Severe alcohol-related life impairment, alcohol dependence (alcoholism), is observed at som...

[Anxiety disorders in childhood and adolescence: clinical and neurobiological aspects].

OBJECTIVE This article reviews the clinical and epidemiological aspects of anxiety disorders in youngsters, as well as current medical and psychological treatment strategies. The role of the neurobiological models possibly involved in the etiology of these disorders is also discussed. SOURCES OF DATA MEDLINE search of papers published in English from 1981 to 2003. The following key words were...

On electroconvulsive therapy in depression : Clinical, cognitive and neurobiological aspects

Memantine and Kynurenic Acid: Current Neuropharmacological Aspects

Glutamatergic neurotransmission, of special importance in the human brain, is implicated in key brain functions such as synaptic plasticity and memory. The excessive activation of N-methyl- D-aspartate (NMDA) receptors may result in excitotoxic neuronal damage; this process has been implicated in the pathomechanism of different neurodegenerative disorders, such as Alzheimer's disease (AD). Mema...